Houston’s offensive line has been a concern, especially early in drives. If Colorado’s defense can disrupt in the backfield, they could force mistakes.

Syracuse will want to tighten up before tougher ACC games; they’ll likely dominate early and keep control. Also, they tend to perform well at home.

@Indy Insights

Notre Dame has the ability to make it a close contest, particularly if their defense can slow down Ohio State and if they can control the clock on offense.

Liberty has been solid this season, with a strong defense and efficient offense. Buffalo has shown some weaknesses, especially on the defensive end, which Liberty could exploit.

North Texas has a strong defense and disciplined playstyle, which should give them the edge over Texas State. The Bobcats may struggle to score against North Texas’s defense.

@Indy Insights

Georgia’s defense, along with their depth and physicality, should be enough to outlast Notre Dame in what could be a close matchup.

LSU’s explosive playmakers on offense give them a strong edge, and Baylor’s defense may struggle to contain them.

Alabama’s playoff experience and balanced attack could be too much for Michigan to handle, despite Michigan’s stout defense.

Ohio State Buckeyes win. Ohio State’s elite offense and playoff experience will likely carry them to victory over a resilient Oregon team.

UNC’s explosive offense, led by a strong quarterback, is likely too much for UConn, who has struggled defensively. The Tar Heels are favorites due to their offensive prowess and superior talent.

Arkansas’ run-heavy offense is tough to stop, but Texas Tech’s high-powered air raid offense could cause problems for Arkansas’ defense. It’s a matchup of styles, with Tech needing to stop the run to win.

Navy’s triple-option attack is hard to prepare for, but Oklahoma’s speed and superior talent give them a clear edge. The Sooners' explosive offense will likely be too much for Navy to handle.

San Jose State’s offense will aim to control the tempo with their passing attack, while South Florida’s defense must focus on limiting big plays. The Bulls’ offense needs to establish the run to balance their attack.